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The decarboxylation of cannabis and CBD... kezako?


Decarboxylation is an essential process for unlocking the full potential of your plant material, whether you're a fan of CBD cooking or not. Although the term may seem complex, mastering it is crucial for cannabis enthusiasts wanting to get the most out of their products. So, what exactly is cannabis decarboxylation?


Simply put, it is a process that activates compounds found in cannabis flowers by exposing them to high temperature. Although this process can occur naturally under the influence of sunlight, it is often necessary to deliberately induce it to achieve optimal results.


Specifically, decarboxylation is a biochemical process in which a carboxyl group (-COOH) is removed from an organic molecule, usually a carboxylic acid, to form a different product. In the context of plants, decarboxylation can take place in various metabolic pathways, including amino acid biosynthesis.




Decarboxylation process


In the case of amino acids, decarboxylation can affect their structure and function in several ways:

1. Formation of neurotransmitters: Certain amino acids, such as glutamate and tyrosine, undergo decarboxylation to form important neurotransmitters like GABA (gamma-aminobutyric acid) from glutamate and dopamine from tyrosine. These neurotransmitters are essential for the transmission of nerve signals in the brain and nervous system.

2. Production of metabolites: Decarboxylation of amino acids can lead to the formation of metabolites important in plant metabolism. For example, decarboxylation of aspartic acid yields alanine, an essential amino acid in many metabolic pathways.

3. Regulation of acid-base balance: Some amino acids can be decarboxylated to help maintain acid-base balance in cells and tissues. For example, decarboxylation of glutamic acid yields glutamate, which is involved in maintaining acid-base balance and plays an important role in amino acid metabolism.


Amino acids are the building blocks of proteins, which are essential for many biological processes in plants, including cell structure, regulation of biochemical reactions, nutrient transport, defense against pathogens, and more. Each amino acid has a specific function in these processes, and their availability and balance in the plant are crucial to maintaining optimal health and functioning.



explanation of the decarboxylation process
Decarboxylation process

 

 

Decarboxylation is often associated with the preparation of cannabis products because it is necessary to activate psychoactive compounds such as THC (tetrahydrocannabinol) naturally found in the plant. However, if you're talking about plants other than cannabis and want to know the effects of decarboxylation on other vape plants, it depends on the specific compounds found in those plants and their reactions to heat.


Natural decarboxylation


Cannabis flowers undergo partial decarboxylation through heat and exposure to air, although this method is not sufficient to achieve high levels of THC and CBD. The drying process, often used to prevent mold growth, also contributes to decarboxylation, although in a limited way.

However, it is important to note that the THC found in flowers can break down into CBN, a cannabinoid known for its relaxing properties, over time. This means that aging flowers can potentially alter their effects, particularly regarding their ability to cause psychoactive sensations.


Some plants contain active compounds that can be activated or modified by the heat of decarboxylation. For example, chamomile, lavender, and sage are often used in aromatherapy and can be vaporized to release their essential oils. The heat of vaporization can help release these aromatic compounds as well as other bioactive compounds found in these plants.


It is important to note that not all plants respond the same way to decarboxylation or vaporization, and it is essential to thoroughly research the specific plants you wish to vaporize to understand their properties and potential effects. Additionally, be sure to follow safety recommendations when using vaporizers to avoid harmful exposure to heat or inhalants.


The decarboxylation of cannabis primarily activates the cannabinoids present in the plant, particularly THC (tetrahydrocannabinol) and CBD (cannabidiol). These compounds are in the form of acids in the plant, such as THCA (tetrahydrocannabinolic acid) and CBDA (cannabidiolic acid), which are non-psychoactive in their acid form.

When heat is applied, such as during vaporization, drying, or the cooking process, these carboxylic acids are decarboxylated, meaning the carboxyl group (-COOH) is removed. This transforms THCA and CBDA into THC and CBD respectively, which are the psychoactive and medicinal forms, respectively, of the cannabinoids.

Decarboxylation also converts other acidic cannabinoids into their active forms, although in lesser proportions compared to THC and CBD. For example, CBGA (cannabigerolic acid) is converted to CBG (cannabigerol) and CBCA (cannabichromenic acid) to CBC (cannabichromene). These cannabinoids also play important roles in the effects and benefits of cannabis, although their concentration is generally lower than that of THC and CBD.

Decarboxylation is therefore a crucial process for maximizing the psychoactive or therapeutic effects of cannabis when used in smoked or vaporized form, or when developing edible or topical cannabis products.


Regarding vaporization, it turns out that slow decarboxylation also allows you to gain flavors compared to decarboxylation which would be done when vaporizing. Unless you have a high-end vaporizer.



CBD decarboxylation in the oven
500g of ground flowers before decarboxylation

1. Activation of Cannabinoids:


Decarboxylation is essential to activate the cannabinoids found in cannabis. For example, heating transforms THCA (tetrahydrocannabinol acid) into THC, the well-known psychoactive compound in cannabis. This maximizes the therapeutic and recreational effects of cannabis.

Obviously if there is no THC at the end it is because there was no THCA at the beginning, still below 0.3% right...


2. Optimization of Therapeutic Effects:


The decarboxylation process is crucial to unlocking the therapeutic potential of cannabis. It allows the conversion of inactive cannabinoid acids into active forms, such as CBDA into CBD, which can improve the effectiveness of medical applications of cannabis.


3. Improved Bio-availability:


Decarboxylation makes cannabinoids more bio-available, making them easier to absorb into the body. This ensures greater effectiveness of cannabis products, whether for recreational or medical consumption.


4. Transformation of Aromas and Flavors:


Besides the medicinal benefits, decarboxylation also influences the sensory properties of cannabis. This process can intensify aromas and flavors, providing a richer and more enjoyable drinking experience.


5. Preparation of Edible Products:


Decarboxylation is essential in creating cannabis edibles. By heating the plant, the cannabinoids are activated, allowing their effective incorporation into recipes such as oils, tinctures or foods.



In conclusion, decarboxylation is a fundamental process for maximizing the therapeutic and recreational benefits of cannabis. It releases active compounds, improves bioavailability, optimizes medicinal effects, and transforms the sensory properties of the plant.


To find out more, consult the FAQ on the question

 

 


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